The difference between a clinical technician and clinical practitioner is in the scope of practice: the need for a bioscience understanding in paramedicine.
“Just teach me what I need to know!” It is usually heard refrain is often spoken by the student allied health for preclinical study science (physiology, anatomy, pharmacology). Here we use clinical scenarios carried out by the second year students Paramedic Practice Bachelor of acute coronary syndromes to show differences in clinical decision making when using clinical reasoning approach to treatment rather than relying exclusively on the approach practice guidelines.
We hope to show that understanding basic bioscience concepts, such as the Frank-Starling mechanism and anatomy and physiology of the autonomic nervous system, is the key to provide good clinical care in response to the patient’s symptoms ambiguous. Students who understand these concepts underlying the patient’s treatment guidelines they will make better clinical decisions and better provide quality care of students who follow the guidelines exclusively.
Our aim is a practical demonstration of the value of a detailed understanding of the human Bioscience in allied health education. As health care providers transition from the “technician” to “practitioner,” the key distinguishing feature of the role is the ability to practice independently, using “best judgment” rather than clinical guidelines (only). Evidence suggests that the management of complex cases require a detailed understanding of bioscience.
Volume 1, Issue 1 of the Mathematical Biosciences is a place for the now-classic paper on the application of the theory of a single disturbance in enzyme kinetics, “On the status of the mathematics of the hypothesis pseudo-steady state kinetics of biochemical” by FG Heineken, HM Tsuchiya and R. Aris. More than 50 years have passed, but the paper continues to be studied and mined for insights.
This perspective discusses both the strengths and weaknesses of the work presented in this paper. For many people, the justification approach to pseudo-steady-state using a single interference theory is the main achievement of this paper. However, there is so much more material here, which laid the foundation for much of biochemistry research of mathematics in the intervening decades
The difference between a clinical technician and clinical practitioner is in the scope of practice: the need for a bioscience understanding in paramedicine.
The Pacific Biosciences de novo assembled genomic dataset of parthenogenesis New Zealand wild populations longhorned ticks, Haemaphysalis longicornis Neumann, 1901.
longhorned tick, Haemaphysalis longicornis, feed on a variety of bird and mammal hosts. Mammalian hosts including cattle, deer, sheep, goats, humans and horses. This tick is known to transmit a number of pathogens that cause tick-borne diseases, and is a vector of a serious outbreak recently theileriosis oriental in New Zealand.
A New Zealand-USA consortium established to sequence, assemble, and annotate the genome of these fleas, use flea obtained from the New Zealand North Island. In New Zealand, the check is considered exclusive parthenogenesis and these properties are considered useful for genome assembly. molecular weight genomic DNA is very high and aligned on the Illumina platform HiSeq4000 long Sequel Bio Pac-read.
Description: The anti-IgY beads were made by cross-linking of bovine IgG anti-IgY antibodies to Protein A/G agarose beads. IgY is the original designation of chicken IgG like immunoglobulin.
IgG Fraction of Immunoprecipitating Rabbit Anti-human PTH (39-84) Sera Lyophilized Powder
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat, Monkey. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF, ChIP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].
Description: Histone deacetylase 3 is a member of the histone deacetylase/acuc/apha family of proteins and is an enzyme that in humans is encoded by the HDAC3 gene. The enzyme has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. The protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. And this gene is regarded as a potential tumor suppressor gene. HDAC3 has an open reading frame of 428 amino acids and shares 53% amino acid identity with HDAC1 and 52% with HDAC2. The catalytic domain of HDAC4 interacts with HDAC3 via the transcriptional corepressor NCOR2. All experimental conditions leading to the suppression of HDAC4 binding to NCOR2 and to HDAC3 resulted in loss of enzymatic activity associated with HDAC4.
Description: HDAC3 (HISTONE DEACETYLASE 3) is a member of the histone deacetylase/acuc/apha family of proteins that is an enzyme that in humans is encoded by the HDAC3 gene. The HDAC3 gene is mapped to 5q31.3. HDAC3 has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. The protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. And this gene is regarded as a potential tumor suppressor gene. HDAC3 has an open reading frame of 428 amino acids and shares 53% amino acid identity with HDAC1 and 52% with HDAC2. The catalytic domain of HDAC4 interacts with HDAC3 via the transcriptional corepressor NCOR2. All experimental conditions leading to the suppression of HDAC4 binding to NCOR2 and to HDAC3 resulted in loss of enzymatic activity associated with HDAC4. HDAC3 recruitment to the genome displays a circadian rhythm in mouse liver.
Twenty-eight SMRT cells produce a total of 21.3 million reads were assembled by Canu in supercomputing node is provided with access to 12 TB of RAM, running continuously for more than 24 days. Dataset final assembly consists of 34 211 contigs with an average contig length of 215 205 bp. Quality was assessed by analysis of genome described BUSCO, the approach provides a quantitative measure for the quality of the assembled genome. More than 95% of BUSCO genes found in the genome assembled sets. Only 48 of the 1,066 genes BUSCO lost and only 9 are present in fragmented condition. Raw sequencing reads and contigs assembled / scaffold archived at the National Center for Biotechnology Information.
Beau
