The difference between a clinical technician and clinical practitioner is in the scope of practice: the need for a bioscience understanding in paramedicine.

The difference between a clinical technician and clinical practitioner is in the scope of practice: the need for a bioscience understanding in paramedicine.

“Just teach me what I need to know!” It is usually heard refrain is often spoken by the student allied health for preclinical study science (physiology, anatomy, pharmacology). Here we use clinical scenarios carried out by the second year students Paramedic Practice Bachelor of acute coronary syndromes to show differences in clinical decision making when using clinical reasoning approach to treatment rather than relying exclusively on the approach practice guidelines.

We hope to show that understanding basic bioscience concepts, such as the Frank-Starling mechanism and anatomy and physiology of the autonomic nervous system, is the key to provide good clinical care in response to the patient’s symptoms ambiguous. Students who understand these concepts underlying the patient’s treatment guidelines they will make better clinical decisions and better provide quality care of students who follow the guidelines exclusively.

Our aim is a practical demonstration of the value of a detailed understanding of the human Bioscience in allied health education. As health care providers transition from the “technician” to “practitioner,” the key distinguishing feature of the role is the ability to practice independently, using “best judgment” rather than clinical guidelines (only). Evidence suggests that the management of complex cases require a detailed understanding of bioscience.


Volume 1, Issue 1 of the Mathematical Biosciences is a place for the now-classic paper on the application of the theory of a single disturbance in enzyme kinetics, “On the status of the mathematics of the hypothesis pseudo-steady state kinetics of biochemical” by FG ​​Heineken, HM Tsuchiya and R. Aris. More than 50 years have passed, but the paper continues to be studied and mined for insights.

This perspective discusses both the strengths and weaknesses of the work presented in this paper. For many people, the justification approach to pseudo-steady-state using a single interference theory is the main achievement of this paper. However, there is so much more material here, which laid the foundation for much of biochemistry research of mathematics in the intervening decades

 The difference between a clinical technician and clinical practitioner is in the scope of practice: the need for a bioscience understanding in paramedicine.
The difference between a clinical technician and clinical practitioner is in the scope of practice: the need for a bioscience understanding in paramedicine.

The Pacific Biosciences de novo assembled genomic dataset of parthenogenesis New Zealand wild populations longhorned ticks, Haemaphysalis longicornis Neumann, 1901.

longhorned tick, Haemaphysalis longicornis, feed on a variety of bird and mammal hosts. Mammalian hosts including cattle, deer, sheep, goats, humans and horses. This tick is known to transmit a number of pathogens that cause tick-borne diseases, and is a vector of a serious outbreak recently theileriosis oriental in New Zealand.

A New Zealand-USA consortium established to sequence, assemble, and annotate the genome of these fleas, use flea obtained from the New Zealand North Island. In New Zealand, the check is considered exclusive parthenogenesis and these properties are considered useful for genome assembly. molecular weight genomic DNA is very high and aligned on the Illumina platform HiSeq4000 long Sequel Bio Pac-read.

Immunoprecipitation IP Lysis Buffer

20831004-3 500 mL
EUR 90.69

Immunoprecipitation Kit (OKRA00051)

OKRA00051 1 kit
EUR 1248
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity:

OKRA00051-1U - Immunoprecipitation Kit

OKRA00051-1U 1kit
EUR 790

OKRA00051-1KIT - Immunoprecipitation Kit

OKRA00051-1KIT 1Kit
EUR 719

Topoisomerase II Immunoprecipitation Kit

TG1035 >50 analyses
EUR 657.6

Control for Immunoprecipitation IgG beads

CIG01-beads 10 assays
EUR 115.44

HiPer® Immunoprecipitation Teaching Kit

HTI016-5PR 1 unit
EUR 75.78
Description: HiPer® Immunoprecipitation Teaching Kit

Immunoprecipitation Kit: Protein A-Agarose

BS688 20Rxn, 20prep
EUR 242.7

Chromatin Immunoprecipitation (ChIP) Assay Kit

TBS8050 25 tests
EUR 560

Immunoprecipitation Kit: Protein A-Sepharose

BS690 20Rxn, 20prep
EUR 237.48

Immunoprecipitation Starter Pack 2 x 2mL - EACH

17600235 EACH
EUR 851.85

EpiQuik Chromatin Immunoprecipitation (ChIP) Kit 

P-2002
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EpiQuik Methylated DNA Immunoprecipitation Kit 

P-2019
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  • 48 Reactions
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  • 48 Reactions

Control for SUM01 Immunoprecipitation IgG beads

CIG03-beads 10 assays
EUR 115.44

Immunoprecipitation Kit: Protein A/G PLUS-Agarose

BS689 20Rxn, 20prep
EUR 237.48

EpiQuik Tissue Chromatin Immunoprecipitation (ChIP) Kit 

P-2003
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EpiQuik Tissue Methylated DNA Immunoprecipitation Kit 

P-2020
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  • 48 Reactions
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Control for Acetylation Immunoprecipitation IgG beads

CIG02-beads 10 assays
EUR 115.44

EpiQuik Hydroxymethylated DNA Immunoprecipitation (hMeDIP) Kit 

P-1038
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  • 96 Reactions
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  • 48 Reactions
  • 96 Reactions

Monoclonal Anti-Rabbit IgG (Light-chain) IgG (adsorbed, for immunoprecipitation/WB)

20160-UL 0.5 ml
EUR 270

Monoclonal Anti-Rabbit IgG (Light-chain) IgG-HRP Conj (adsorbed, for immunoprecipitation/WB)

20160-HRP 0.5 ml
EUR 315.6

Monoclonal Anti-Rabbit IgG (Light-chain) IgG-Biotin Conj (adsorbed, for immunoprecipitation/WB)

20160-BT 0.5 ml
EUR 315.6

Bovine Anti-Chicken IgY Beads for immuno-precipitation

XG-6134 1 mL
EUR 546.72
Description: The anti-IgY beads were made by cross-linking of bovine IgG anti-IgY antibodies to Protein A/G agarose beads. IgY is the original designation of chicken IgG like immunoglobulin.

Hdac3/ Rat Hdac3 ELISA Kit

ELI-27737r 96 Tests
EUR 1063.2

HDAC3

E8ET1610-5 100ul
EUR 275
Description: Available in various conjugation types.

HDAC3

CSB-CL010239HU 10 μg plasmid + 200μl Glycerol Ask for price

HDAC3

PC-363 Polyclonal Ask for price

HDAC3

60B770 0.1mg
EUR 259

Rabbit Anti HDAC3 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot,IHC,Immunofluorescence)

IRBAMLHDAC3AP237120UL each
EUR 346
Description: Rabbit Anti HDAC3 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot,IHC,Immunofluorescence)

Rabbit Anti HDAC3 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot,IHC,Immunofluorescence)

IRBAMLHDAC3AP237200UL each
EUR 509
Description: Rabbit Anti HDAC3 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot,IHC,Immunofluorescence)

HDAC3 siRNA

20-abx919179
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  • 15 nmol
  • 30 nmol

HDAC3 siRNA

20-abx919180
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  • 15 nmol
  • 30 nmol

HDAC3 (untagged)-Human histone deacetylase 3 (HDAC3)

SC112704 10 µg Ask for price

HDAC3 Protein 

E24006
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  • 50 µg
  • 50 ul

HDAC3 Antibody

ABD6862 100 ug
EUR 525.6

HDAC3 Antibody

8C0224 50ug
EUR 368
Description: HDAC3 Antibody

HDAC3 Antibody

6603-100 each
EUR 405.6

HDAC3 Antibody

6603-30T each
EUR 175.2

HDAC3 antibody

10R-10389 100 ug
EUR 451
Description: Mouse monoclonal HDAC3 antibody

HDAC3 antibody

10R-2003 100 ul
EUR 503
Description: Mouse monoclonal HDAC3 antibody

HDAC3 antibody

10R-2004 100 ul
EUR 503
Description: Mouse monoclonal HDAC3 antibody

HDAC3 antibody

20R-2774 50 ug
EUR 269
Description: Rabbit polyclonal HDAC3 antibody

HDAC3 Antibody  

21660 100ul
EUR 319

HDAC3 Antibody  

21660-100ul 100ul
EUR 302.4

HDAC3 Antibody  

21660-50ul 50ul
EUR 224.4

HDAC3 Antibody

32620-100ul 100ul
EUR 302.4

HDAC3 Antibody

31216 100ul
EUR 319

HDAC3 Antibody

31216-100ul 100ul
EUR 302.4

HDAC3 Antibody

31216-50ul 50ul
EUR 224.4

HDAC3 Antibody

33400 100ul
EUR 319

HDAC3 Antibody

33400-100ul 100ul
EUR 302.4

HDAC3 Antibody

33400-50ul 50ul
EUR 224.4

HDAC3 Antibody

3603-100 each
EUR 379.2

HDAC3 Antibody

3603-30T each
EUR 175.2

HDAC3 Antibody

48964 100ul
EUR 499

HDAC3 Antibody

48964-100ul 100ul
EUR 399.6

HDAC3 Antibody

48964-50ul 50ul
EUR 286.8

HDAC3 Antibody

CSB-PA967736- each
EUR 402
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

HDAC3 Antibody

CSB-PA967736-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

HDAC3 Antibody

E031216 100μg/100μl
EUR 255
Description: Available in various conjugation types.

HDAC3 Antibody

E033400 100μg/100μl
EUR 255
Description: Available in various conjugation types.

HDAC3 Antibody  

E021660 100μg/100μl
EUR 255
Description: Available in various conjugation types.

HDAC3 Antibody

E11-0224C 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

E10-20259 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

E10-20260 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

E18-0733-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

HDAC3 Antibody

E18-0733-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

E18-5349-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

HDAC3 Antibody

E18-5349-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

E18-6016-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

HDAC3 Antibody

E18-6016-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

E19-6862 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

E230006-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

HDAC3 Antibody

E230006-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

1-CSB-PA899967
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  • 100ul
  • 50ul
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000

HDAC3 Antibody

CSB-PA916163- each
EUR 402
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

HDAC3 Antibody

CSB-PA916163-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

HDAC3 Antibody

DF6862 200ul
EUR 420

HDAC3 Antibody

DF6862-100ul 100ul
EUR 280

HDAC3 Antibody

DF6862-200ul 200ul
EUR 350

HDAC3 Antibody

E220032-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

HDAC3 Antibody

E220032-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

E552007-1-PU 100ug
EUR 295
Description: Available in various conjugation types.

HDAC3 Antibody

E92139 100ul
EUR 255
Description: Available in various conjugation types.

HDAC3 Antibody

E307498 100ug/200ul
EUR 275
Description: Available in various conjugation types.

HDAC3 Antibody

E2220011 100ug
EUR 225
Description: Available in various conjugation types.

HDAC3 Antibody

BF0230 200ul
EUR 540

HDAC3 Antibody

BF0230-100ul 100ul
EUR 350

HDAC3 Antibody

BF0230-200ul 200ul
EUR 450

HDAC3 Antibody

BF0230-50ul 50ul
EUR 250

HDAC3 antibody

70R-14137 100 ug
EUR 519
Description: Affinity purified Rabbit polyclonal HDAC3 antibody

HDAC3 antibody

70R-17706 50 ul
EUR 289
Description: Rabbit polyclonal HDAC3 antibody

HDAC3 antibody

70R-11943 100 ug
EUR 343
Description: Rabbit polyclonal HDAC3 antibody

HDAC3 antibody

70R-31225 100 ug
EUR 294
Description: Rabbit polyclonal HDAC3 antibody

HDAC3 antibody

70R-33611 100 ug
EUR 294
Description: Rabbit polyclonal HDAC3 antibody

Hdac3 antibody

70R-8546 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal Hdac3 antibody

HDAC3 Antibody

AF0733 200ul
EUR 420

HDAC3 Antibody

AF6016 200ul
EUR 420

HDAC3 Antibody

AF6016-100ul 100ul
EUR 280

HDAC3 Antibody

AF6016-200ul 200ul
EUR 350

HDAC3 Antibody

AF5349 200ul
EUR 420

HDAC3 Antibody

AF5349-100ul 100ul
EUR 280

HDAC3 Antibody

AF5349-200ul 200ul
EUR 350

HDAC3 Antibody

1-CSB-PA004117
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  • 100ug
  • 50ug
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat, Monkey. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000

HDAC3 Antibody

1-CSB-PA010239GA01HU
  • Ask for price
  • Ask for price
  • 150ul
  • 50ul
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

HDAC3 Antibody

1-CSB-PA010239LA01HU
  • Ask for price
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  • 100ug
  • 50ug
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF, ChIP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200

HDAC3 Antibody

1-CSB-PA002880
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  • 100ug
  • 50ug
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000

HDAC3 Antibody

ABF5349 100 ug
EUR 525.6

HDAC3 Antibody

ABF6016 100 ug
EUR 525.6

HDAC3 Antibody

ABF0733 100 ug
EUR 525.6

Hdac3 Antibody

GWB-MP264C 50ug Ask for price

HDAC3 Antibody

F42873-0.08ML 0.08 ml
EUR 140.25
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].

HDAC3 Antibody

F42873-0.4ML 0.4 ml
EUR 322.15
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].

HDAC3 Antibody

R34813-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Histone deacetylase 3

HDAC3 Antibody

RQ4727 100ul
EUR 356.15
Description: Histone deacetylase 3 is a member of the histone deacetylase/acuc/apha family of proteins and is an enzyme that in humans is encoded by the HDAC3 gene. The enzyme has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. The protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. And this gene is regarded as a potential tumor suppressor gene. HDAC3 has an open reading frame of 428 amino acids and shares 53% amino acid identity with HDAC1 and 52% with HDAC2. The catalytic domain of HDAC4 interacts with HDAC3 via the transcriptional corepressor NCOR2. All experimental conditions leading to the suppression of HDAC4 binding to NCOR2 and to HDAC3 resulted in loss of enzymatic activity associated with HDAC4.

HDAC3 Antibody

RQ5284 100ug
EUR 356.15
Description: HDAC3 (HISTONE DEACETYLASE 3) is a member of the histone deacetylase/acuc/apha family of proteins that is an enzyme that in humans is encoded by the HDAC3 gene. The HDAC3 gene is mapped to 5q31.3. HDAC3 has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. The protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. And this gene is regarded as a potential tumor suppressor gene. HDAC3 has an open reading frame of 428 amino acids and shares 53% amino acid identity with HDAC1 and 52% with HDAC2. The catalytic domain of HDAC4 interacts with HDAC3 via the transcriptional corepressor NCOR2. All experimental conditions leading to the suppression of HDAC4 binding to NCOR2 and to HDAC3 resulted in loss of enzymatic activity associated with HDAC4. HDAC3 recruitment to the genome displays a circadian rhythm in mouse liver.

HDAC3 Inhibitor

T36575-10mg 10mg Ask for price
Description: HDAC3 Inhibitor

HDAC3 Inhibitor

T36575-1g 1g Ask for price
Description: HDAC3 Inhibitor

HDAC3 Inhibitor

T36575-1mg 1mg Ask for price
Description: HDAC3 Inhibitor

HDAC3 Inhibitor

T36575-50mg 50mg Ask for price
Description: HDAC3 Inhibitor

HDAC3 Inhibitor

T36575-5mg 5mg Ask for price
Description: HDAC3 Inhibitor

HDAC3 (GFP-tagged) - Human histone deacetylase 3 (HDAC3)

RG200605 10 µg Ask for price

Hdac3 (untagged) - Mouse histone deacetylase 3 (Hdac3), (10ug)

MC208653 10 µg Ask for price

Immunoproteasome inhibitor 1

T61320-10mg 10mg Ask for price
Description: Immunoproteasome inhibitor 1

Immunoproteasome inhibitor 1

T61320-1g 1g Ask for price
Description: Immunoproteasome inhibitor 1

Immunoproteasome inhibitor 1

T61320-1mg 1mg Ask for price
Description: Immunoproteasome inhibitor 1

Immunoproteasome inhibitor 1

T61320-50mg 50mg Ask for price
Description: Immunoproteasome inhibitor 1

Immunoproteasome inhibitor 1

T61320-5mg 5mg Ask for price
Description: Immunoproteasome inhibitor 1

HDAC3 Mouse mAb

27125 100ul
EUR 319

HDAC3 Mouse mAb

E2220248 100ul
EUR 225
Description: Available in various conjugation types.

HDAC3 Mouse mAb

A2603-100ul 100 ul
EUR 460.8

HDAC3 Mouse mAb

A2603-200ul 200 ul
EUR 664.8

HDAC3 Mouse mAb

A2603-20ul 20 ul Ask for price

HDAC3 Mouse mAb

A2603-50ul 50 ul
EUR 318

HDAC3 Assay Kit

55R-1377 100 assays
EUR 527
Description: Assay Kit for detection of HDAC3 in the research laboratory

HDAC3 Rabbit mAb

58888 100ul
EUR 339

HDAC3 Rabbit pAb

A12542-100ul 100 ul
EUR 369.6

HDAC3 Rabbit pAb

A12542-200ul 200 ul
EUR 550.8

HDAC3 Rabbit pAb

A12542-20ul 20 ul
EUR 219.6

HDAC3 Rabbit pAb

A12542-50ul 50 ul
EUR 267.6

HDAC3 Rabbit pAb

E2310148 100ul
EUR 225
Description: Available in various conjugation types.

HDAC3 Rabbit pAb

E2381151 100ul
EUR 225
Description: Available in various conjugation types.

HDAC3 Rabbit mAb

E2R24536 100ul
EUR 255
Description: Available in various conjugation types.

Twenty-eight SMRT cells produce a total of 21.3 million reads were assembled by Canu in supercomputing node is provided with access to 12 TB of RAM, running continuously for more than 24 days. Dataset final assembly consists of 34 211 contigs with an average contig length of 215 205 bp. Quality was assessed by analysis of genome described BUSCO, the approach provides a quantitative measure for the quality of the assembled genome. More than 95% of BUSCO genes found in the genome assembled sets. Only 48 of the 1,066 genes BUSCO lost and only 9 are present in fragmented condition. Raw sequencing reads and contigs assembled / scaffold archived at the National Center for Biotechnology Information.

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