Long-Term Effect of Ultrathin-Strut Versus Thin-Strut Drug-Eluting Stents in Patients With Small Vessel Coronary Artery Disease Undergoing Percutaneous Coronary Intervention: A Subgroup Analysis of the BIOSCIENCE Randomized Trial.
Orsiro randomized trials evaluating the biodegradable polymer sirolimus-eluting stent (BP-SES; 60 and 80 pM stent strut thickness to diameter ≤3 and> 3 mm, respectively) did not stratify according to size of the ship and failed to determine the impact of ultrathin- strut thickness the long-term clinical outcomes compared with a durable polymer everolimus-eluting stent (DP-EES).
We are trying to assess the long-term effects of ultrathin-strut (60 m) BP-SES compared to thin-strut (81 m) DP-ees on long-term outcomes in patients undergoing percutaneous coronary revascularization for small boats disease.In subgroup analysis of a randomized, multicenter, noninferiority trial Bioscience, patients with stable coronary artery disease or acute coronary syndrome were randomly assigned to treatment with BP-SES or DP-EES grouped by the size of the vessel (≤3 mm vs> 3 mm) as a replacement for comparing patients treated with ultrathin-thin-strut strut vs. drug-eluting stent. The primary endpoint is target lesion failure, a composite of cardiac death, target vessel myocardial infarction and clinically indicated target lesion revascularization, within 5 years.
RESULTS Among the 2109 patients, 1234 (59%) treated for small vessel disease. At 5 years, the target lesion failure occurred in 124 patients (cumulative incidence, 22.3%) were treated with ultrathin-strut BP-SES and 109 patients (18.3%) were treated with a thin-strut DP-EES (rate ratio, 1 , 22; 95% CI, 0.94 to 1.58; P = 0.13).
The cumulative incidence of cardiac death, target vessel myocardial infarction and clinically indicated target lesion revascularization and definite stent thrombosis at 5 years was similar in patients treated with ultrathin-strut BP-SES and thin-strut DP-EES. After adjustment for potential confounders, there was no significant interaction between treatment effect size of the ship and BP-SES compared to DP-EES. We found no significant differences in clinical outcomes throughout the 5 years between patients with small vessel disease treated with ultrathin-strut BP-SES compared to thin-strut DP-EES.URL
Long-Term Effect of Ultrathin-Strut Versus Thin-Strut Drug-Eluting Stents in Patients With Small Vessel Coronary Artery Disease Undergoing Percutaneous Coronary Intervention: A Subgroup Analysis of the BIOSCIENCE Randomized Trial.
ALFA-tag is a very versatile tool for nanobody-based bioscience applications.
Special epitope tags are widely used to detect, manipulate or purify proteins, but often they have limited flexibility. Here, we introduce ALFA-tags, epitope tags are designed rationally serves a very broad spectrum of applications in life sciences while outperformed tag was established as ha-, FLAG®- or myc-tag. ALFA-forms of α-helix tag is small and stable despite its position in the target protein functional in prokaryotic and eukaryotic hosts.
We characterize nanobody (NbALFA) binding protein ALFA-tag of the original specimen or stick with low picomolar affinity. It is suitable for super-resolution microscopy, immunoprecipitations and Western blotting, and also allows the in vivo detection of protein. We were shown a complex crystal structure that allows us to design a mutant nanobody (NbALFAPE) which allows the efficient purification step original ALFA-tagged proteins, complexes and even whole living cells using a peptide elution under physiological conditions.
Recent developments in genotyping technology coupled with the growing desire to characterize genomic variation in populations of Anopheles an opportunity to develop more effective strategies for the genotypes of high-throughput screening. A major obstacle of this objective is the extraction of nucleic acids.
Should the Human Histone Deacetylase 1 (HDAC1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Histone Deacetylase 1 (HDAC1) in samples from tissue homogenates, cell lysates or other biological fluids.
Should the Human Histone Deacetylase 1 (HDAC1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Histone Deacetylase 1 (HDAC1) in samples from tissue homogenates, cell lysates or other biological fluids.
Should the Mouse Histone Deacetylase 1 (HDAC1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Histone Deacetylase 1 (HDAC1) in samples from tissue homogenates, cell lysates or other biological fluids.
Should the Mouse Histone Deacetylase 1 (HDAC1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Histone Deacetylase 1 (HDAC1) in samples from tissue homogenates, cell lysates or other biological fluids.
Should the Rat Histone Deacetylase 1 (HDAC1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Histone Deacetylase 1 (HDAC1) in samples from tissue homogenates, cell lysates or other biological fluids.
Should the Rat Histone Deacetylase 1 (HDAC1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Rat Histone Deacetylase 1 (HDAC1) in samples from tissue homogenates, cell lysates or other biological fluids.
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/10000
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:10-1:50
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100
Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF, ChIP; Recommended dilution: IHC:1:20-1:200, IF:1:100-1:500
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100
Description: A polyclonal antibody against HDAC1. Recognizes HDAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HDAC1 . This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HDAC1 . This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HDAC1 . This antibody is tested and proven to work in the following applications:
Immunogen information: Synthesized peptide derived from the Internal region of human HDAC1
Applications tips:
Description: A polyclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human HDAC1
Immunogen information: Synthesized peptide derived from the Internal region of human HDAC1
Applications tips:
Description: A polyclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human HDAC1
Immunogen information: Synthesized peptide derived from the Internal region of human HDAC1
Applications tips:
Description: A polyclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human HDAC1
Immunogen information: Synthesized peptide derived from human HDAC1 around the non-phosphorylation site of S421
Applications tips:
Description: A polyclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human HDAC1 around the non-phosphorylation site of S421
Immunogen information: Synthesized peptide derived from human HDAC1 around the non-phosphorylation site of S421
Applications tips:
Description: A polyclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human HDAC1 around the non-phosphorylation site of S421
Immunogen information: Synthesized peptide derived from human HDAC1 around the non-phosphorylation site of S421
Applications tips:
Description: A polyclonal antibody for detection of HDAC1 from Human, Mouse, Rat. This HDAC1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human HDAC1 around the non-phosphorylation site of S421
Description: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Description: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Description: HDAC1 is a protein encoded by the HDAC1 gene which is approximately 55,1 kDa. HDAC1is localised to the nucleus. It is involved in notch signalling pathways and p53 signalling. This protein falls under the histone deacetylase family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation plays a key role in the regulation of eukaryotic gene expression. It also interacts with a retinoblastoma tumour-suppressor protein which forms a complex that is key in controlling cell proliferation and differentiation. HDAC1 is ubiquitously expressed with higher levels in heart, pancreas and testis. Mutations in the HDAC1 gene may result in Rett syndrome. STJ97722 was developed from clone 4E1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of HDAC1.
Here, we test the feasibility of using an integral part of the foot of mosquitoes as the source of template DNA for whole genome amplification (WGA) by primer-extension preamplification. We use Agena Biosciences MassARRAY (®) platform (formerly Sequenom) to genotype SNPs 78 to 265 feet WGA samples.
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 ELISA Kit)
Human Histone Deacetylase 1 (HDAC1) ELISA Kit  ELISA Kit)
Mouse Histone Deacetylase 1 (HDAC1) ELISA Kit  ELISA Kit)
Rat Histone Deacetylase 1 (HDAC1) ELISA Kit )
Immunoprecipitation Kit (OKRA00051) 
Topoisomerase II Immunoprecipitation Kit 
Hdac1/ Rat Hdac1 ELISA Kit  Kit)
EpiQuik Chromatin Immunoprecipitation (ChIP) Kit 
EpiQuik Methylated DNA Immunoprecipitation Kit 
Immunoprecipitation Kit: Protein A-Agarose 
Immunoprecipitation Kit: Protein A-Sepharose 
Coelenterazine ip 
HDAC1 Antibody 
HDAC1 antibody 
HDAC1 Protein 
HDAC1 siRNA 
pCMV-HDAC1 
pOTB7-HDAC1 
anti-HDAC1 
IP-10/ Rat IP- 10 ELISA Kit  Kit)
EpiQuik Hydroxymethylated DNA Immunoprecipitation (hMeDIP) Kit  Kit)
EpiQuik Tissue Chromatin Immunoprecipitation (ChIP) Kit 
EpiQuik Tissue Methylated DNA Immunoprecipitation Kit 
IP 10 antibody 
IP-10 Antibody 
IP Lysis Buffer 
IP Receptor Antibody 
rHu IP-10 
Immunoprecipitation Kit: Protein A/G PLUS-Agarose 
HDAC1 Blocking Peptide 
HDAC1 Polyclonal Antibody 
Polyclonal HDAC1 Antibody 
HDAC1 Mouse mAb 
HDAC1 Monoclonal Antibody )
HDAC1 antibody (Ser421)  Antibody)
HDAC1 (pS421) Antibody 
HDAC1 Conjugated Antibody 
HDAC1-specific Antibody 
HDAC1 cloning plasmid 
anti- HDAC1 antibody 
Anti-HDAC1 Antibody )
anti-HDAC1 (3E1) 
Anti-HDAC1 antibody 
Recombinant Human HDAC1 )
Anti-HDAC1 (1D6) )
Anti-HDAC1 (5A11) )
Anti-HDAC1 (5C11) )
Anti-HDAC1 (5C4) 
IP-10, human recombinant 